Ludwig Lundberg
PhD project: Exploring and increasing the bioactivity of probiotics through alterations in the production parameters.
Limosilactobacillus reuteri DSM 17938 is among the most scientifically well-documented probiotic strains in the world. Clinical trials have shown that the strain is able to ameliorate infantile colic among other disorders. How probiotic strains such as DSM 17938 are produced impacts the bioactivity to great extent, and in this project these bioactive compounds and how the bacteria is best produced in order to maintain high biological activity is studied. The project studies secreted bioactive compounds such as probiotic membrane vesicles released by the bacteria in models for host-interactions but also interactions between probiotic strains and how, for instance, cocultivation affects their bioactive properties. The project is one of the LivsID industrial doctoral projects and it is made in collaboration with BioGaia.
Poster – Multifunctional membrane vesicles produced by L. reuteri DSM 17938 and their potential link to relief of infantile colic
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Supervisors
Main supervisor: Stefan Roos, Department of Molecular Sciences, SLU. Sebastian Håkansson, BioGaia AB. Caroline Linninge, BioGaia AB. Hans Jonsson, Department of Molecular Sciences, SLU.
Location
Department of Molecular Sciences, SLU
About Ludwig
Industrial PhD student at SLU and holds a MSc in Experimental and Medical Biosciences from the University of Linköping. I enjoy being an industrial PhD-student as it allows for close interactions with the academia and the industry. Working with innovation and relating our research to potential intellectual property is one of the best parts of being an industrial PhD student at BioGaia.
Contact
Ludvig Lundberg, ludwig.lundberg@slu.se