Ludwig Lundberg

PhD project title: Exploring and increasing the bioactivity of probiotics through alterations in the production parameters

Short description of the project

Limosilactobacillus reuteri DSM 17938 is one of the most scientifically well‑documented probiotic strains in the world, with clinical trials demonstrating beneficial effects such as alleviation of infantile colic. The way probiotic strains are produced has a substantial impact on their bioactivity.

This project investigates which bioactive compounds are secreted—such as probiotic membrane vesicles—and how production parameters influence their formation and stability. It also explores interactions between probiotic strains, including how co‑cultivation affects their biological activity. The project is part of the LivsID industrial doctoral programme and is conducted in collaboration with BioGaia.

Supervisors

Main supervisor

• Stefan Roos, Department of Molecular Sciences, SLU

Co-supervisors

• Sebastian Håkansson, BioGaia AB
• Caroline Linninge, BioGaia AB
• Hans Jonsson, Department of Molecular Sciences, SLU

Location

Department of Molecular Sciences, Swedish University of Agricultural Sciences (SLU

I am an industrial PhD student at SLU and hold an MSc in Experimental and Medical Biosciences from Linköping University. I enjoy working at the intersection of academia and industry, where research can be directly connected to innovation and potential intellectual property. Collaborating closely with BioGaia gives me the opportunity to work on applied science with real‑world relevance, which I find both motivating and inspiring.